Featuring Mandiant’s Nick Pelletier, Managing Director, and Ben Trachtenberg, Manager—both founding mentors of the San Diego Cyber Clinic—this discussion explores the anatomy of recent cyberattacks and the evolving threat landscape. Drawing on insights from Mandiant’s 2025 investigations, they discuss emerging attack vectors including public-facing vulnerabilities, voice phishing and social engineering, cloud compromises, supply chain attacks, and state-sponsored espionage, along with the growing role of AI in cyberattacks. They also share practical insights on detection, vulnerability management, backup resilience, and protecting organizations against today’s most persistent threats.